prepFAST 3 – High Throughput Autodilution & Autocalibration System

The best way to improve metals laboratory workflows.
Supported by two decades of laboratory automation experience, prepFAST 3 simplifies autodilution, eliminates sample re-runs, and enhances laboratory productivity.

Automation by the Experts

prepFAST 3 combines high-throughput FAST analysis with third generation autodilution to automate sample preparation for ICP and ICPMS. prepFAST 3 performs FAST analysis of undiluted samples and dilutes any sample or standard as needed up to 400x. Dilution functions include instrument autocalibration, prescriptive inline sample dilution (e.g. 10x or 25x) and reactive QC-driven dilutions such as overrange and internal standard out-of-range dilutions. Anti-clogging FilterProbe with backflush, SampleSense 3, and other new technologies make prepFAST 3 the best way to improve metals laboratory workflows.

FAST prepFAST – Ultra-high throughput for undiluted samples and full autodilution capabilities for both prescriptive and QC-driven dilution.
Anti-clogging FilterProbe with BackFlush – FilterProbe catches sample particles and fibers, then automatically syringe-backflushes after each sample. Prevents clogs, extends analytical runs, reduces scheduled maintenance for days or even weeks.
Multiposition Magnetic SnapValves – Easy valve installation and maintenance. No tools required.
SampleSense 3 – Autocalibrated to sense all solvents and sample types. Automatically detects the sample and adjusts timing. One simple method for all analyses.

Syringe Injected Bubble (SIB) – Separates sample from the analytical carrier to extend the available analysis time.
Clean3V Enclosure – Three vertical sliding doors provide easy access to sample racks at any time.
Superior Autosampler – DXCi Autosampler provides the highest speeds & autocorrecting probe positioning for highest productivity. Available in 2, 4, 8, and 14-rack capacities.
Compact Footprint – The world’s smallest autodilution system, conserving valuable bench space for your lab.
Seamless Software Integration - Fully compatible with your ICP/ICPMS software.

Features Diagram Featured Components Analytical Steps AutoBench & ULPA Options Resources

prepFAST 3 Features Diagram

Featured Diagram for prepFAST 3

FAST prepFAST

prepFAST 3 utilizes ESI's proven prepFAST IC technology for both ultra-high throughput and elemental speciation, and applies it to routine high-throughput applications, such as environmental testing, mining, clinical and other important analysis applications.

prepFAST 3 provides high-throughput sample analysis alongside autodilution and autocalibration. The system responds to the dilution factor specified in the ICP/ICPMS software, directing undiluted samples to the sample line for FAST high-throughput analysis, saving valuable time. Samples with a dilution factor (DF) greater than 1 are directed to the dilution line then diluted before analysis.

FAST - Undiluted samples loaded into sample line and FAST injected
prepFAST - Samples requiring dilution are loaded into dilution line, automatically diluted, and injected
Shortened probe - Probe valve design uses shortened autosampler probe, expediting sample loading for both sample flow paths

FAST prepFAST

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FilterProbe with BackFlush - Anti-clogging

The innovative FilterProbe effectively blocks large particulates from entering the sample path, significantly reducing maintenance caused by a clogged nebulizer or valve. Syringe-driven backflushing automatically clears the sample path before the next sample is analyzed. By automating this step, operators can focus on other tasks without worrying about potential blockages or downtime due to maintenance.

Automatically backflushes to clean the filter while each sample is analyzed--no additional time required
Prevents valve and nebulizer clogging to reduce weekly valve-cleaning maintenance
Increases longevity of components

Part Number	Description
FPA-DX10	FilterProbe Assembly, 1 mm. Inlcudes FPT-DX10 FilterProbe Tip and FPF-MFA CTFE Filter
FPT-DX10	FilterProbe Tip, 1 mm i.d. PTFE with carbon-fiber support. For ESI DX Autosampler. (Filter not included.)
FPF-MFA	CTFE replacement filter for FilterProbe, Type A. 1/4-28 M-F

FilterProbe with Backflush

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SampleSense 3

The third generation of SampleSense comes standard with prepFAST 3. SampleSense 3 technology detects the sample and triggers the ICPMS analysis, eliminating timing parameters, improving throughput, and reducing sample consumption.

No need for sensor adjustment with SampleSense 3
It works for all chemicals automatically
The new design has easy-to-clean valve internals for labs that have scheduled valve-cleaning procedures

SampleSense 3

Multiposition Magnetic SnapValve

prepFAST 3 is equipped with innovative Magnetic SnapValves to streamline installation and maintenance. Simply snap on and off with your hands, eliminating the need for tools. All valve ports are marked with clear labels to improve user experience and minimize confusion when attaching lines.

Innovative Technology - patented magnetic attachment
Easy Installation - Simply snap on and off, no tools needed to remove from drive
Simple Maintenance - Cleaning procedure takes seconds

Magnetic SnapValve

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Clean3V Enclosures

Clean3V enclosures provide a clean sample environment, shielding the laboratory from acidic vapors. Featuring vertical sliding doors that allow convenient access from three sides, Clean3V enclosures further minimize the system footprint, preserving valuable bench space.

Provides clean sample environment
Protects laboratory from potentially harmful vapors
Easily access samples with three vertical sliding doors
ULPAclean 10 option available for ultraclean sample environment

Clean3V Enclosure Only	Description
C3V2	Clean3V Enclosure for 2DX ESI Autosampler with vertical sliding doors
C3V4	Clean3V Enclosure for 4DX ESI Autosampler with vertical sliding doors
C3V8	Clean3V Enclosure for 8DX ESI Autosampler with vertical sliding doors
C3V14	Clean3V Enclosure for 14DX ESI Autosampler with vertical sliding doors

Autosampler Enclosure

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DXCi Superior Autosamplers

The DXCi autosampler is a durable, streamlined, integrated automation system with fully expandable hardware and software supporting inorganic and organic applications. The system configurations range from a basic high-performance autosampler to a complete, easy-to-use, on-line sample preparation system.

Autocorrecting - Automatically goes to the correct sample position, even if the probe or arm is accidentally obstructed
Reports obstructed locations to the instrument software
Dual flowing rinse station with waste location for filter backflush
Highest probe accuracy with anti-kinking line – optimal for microplates and small sample vials
Available in 2DXCi, 4DXCi, 8DXCi and 14DXCi autosampler models

Part Number	Description
2DXCi	Two rack high-speed autosampler with autocorrecting capabilities
4DXCi	Four rack high-speed autosampler with autocorrecting capabilities
8DXCi	Eight rack high-speed autosampler with autocorrecting capabilities
14DXCi	Fourteen rack high-speed autosampler with autocorrecting capabilities

DXCi Superior Autosampler

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prepFAST 3 Analytical Steps

prepFAST 3 is equipped with innovative FAST prepFAST technology, allowing for rapid undiluted sample analysis or intelligent autodilution. Both analytical flowpaths can be observed below:

FAST Ultra-high Throughput (Undiluted Samples)

STEP: 1 Sample is loaded into the FAST Sample Line

Sample is loaded into the FAST Sample Line

STEP: 2 Sample is injected and analyzed

Sample is injected and analyzed

Autodilution/Autocalibration (Samples and Standards with Dilution Factor > 1)

STEP: 1 Sample is loaded into the Dilution Line

Sample is loaded into the Dilution Line

STEP: 2 Sample is syringe diluted into Sample Line

Sample is syringe diluted into Sample Line

STEP: 3 Sample is injected and analyzed

Sample is injected and analyzed

Dual Monitor Metal-free AutoBench

The dual-monitor metal-free AutoBench option for prepFAST 3 is an all-in-one solution for your laboratory. AutoBench holds the ICP or ICPMS, prepFAST 3, and includes a built-in DXCi autosampler. Engineered with a compact footprint to optimize space utilization, this system enhances laboratory efficiency while offering ample storage capacity. Its innovative waste containment unit and vacuum pump silencing cabinet not only promote safety but also contribute to a quieter and more streamlined workspace.

Comprehensive Benefits:

All-in-one solution
- Extend analysis runs and maximize efficiency with high-capacity autosamplers
- Improve lab safety with innovative waste contaiment cabinet
- Seamlessly integrate with ICP or ICPMS
Metal-free components
- Doors, drawers, and benchtop are completely metal-free. Even the hinges are metal-free and corrosion-free.
- Enhance sensitivity, improve detection limits, and improve reproducibility
- Extend lifespan and reduce maintenance costs
Compact footprint
- Dual screen monitor with stand-up desk concept. Save valuable lab floorspace with clever space utilization.
- 4-rack and 8-rack versions. Includes, computer, ICP/ICPMS, waste bottle, vacuum pump, and more

Metal-free AutoBench

Shown: Dual Monitor Metal-free AutoBench8

ULPA Air Filter

The ULPAclean 10 (Ultra-Low Particle Arrester) filter creates a clean, positive pressure environment for samples and standards and prevents airborne contamination. It removes 99.9995% of 0.1 µm or larger particles. The mounting plate is compatible with all DX autosampler Clean3V enclosures.

Part #	Description
ULPA10	ULPAclean-10 filter for ESI Clean3V Enclosures

Power	Air Volume
24VDC	1.0 (m³/min) or 0.5 (m³/min)

ULPAclean 10 Filter

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Sample Racks & Vials

From 96-well microplates to 100 ml volumetric flasks, ESI offers both standard autosampler racks as well as an extensive variety of specialized racks to accommodate almost any vial, vessel or bottle imaginable for automated sample analysis. DX Series autosamplers offer flexible rack configurations that permit almost any sample size, from micro vials up to 500 mL and larger bottles.