microFAST Single Cell - Complete Solution for Single Cell ICPMS Applications

The ability to introduce single cells into an ICPMS and measure the elemental content in each cell, or tagged to each cell, accurately takes a dedicated, well-designed sample introduction system. Having this ability allows for investigators to better understand how much of a specific nanoparticle, metallodrug, or metal-based compound enters the cell. These cells or nanoparticles will vary in size from a few nm’s up to a few 100 μm’s. The typical cell types of interest will vary and with that the stability of the cell-line also varies, such that a gentle, controlled nebulization must be employed in order to not disrupt or lyse the cell.

Complete system includes:
  • microFAST Single Cell Autosampler
  • Offered in two different orientations - left-handed or right-handed
  • Single Cell Introduction Kit
  • CytoNeb
  • CytoSpray
  • One-piece torch
Benefits:
  • Flexible sample volumes - μL to mL of sample
  • Ensure cells stay intact, no cell lysing
  • Low pressure sample introduction
  • High transport efficiency

Capabilities  Applications  Accessories  Specifications

Single Cell Sample Introduction Kit:

CytoNeb

  • Meinhard quartz High Efficiency Nebulizer
  • Designed specifically for single cell and nanoparticle analysis by ICPMS
  • Low internal volume
  • Low backpressure (1 - 50 μL/min = < 50 psi)
  • Lowest dead volume
  • Equipped with easy to use quick connects
CytoSpray
  • Spray chamber designed specifically for single cell and nanoparticle applications
  • High-transport efficiency
  • Separate make-up gas for better transport efficiency
  • Includes one-piece ICPMS torch for simple and direct connection to the CytoSpray
One-piece torch
  • Designed for simple and direct coupling to the CytoSpray chamber
  • Torch available for each ICPMS model

Learn More about Single Cell Sample Introduction Kit

Single Cell Sample Introduction Kit Single Cell Sample Introduction Kit Single Cell Sample Introduction Kit

Septum Piercing Kit

The SPP Kit adds the capability of sampling from vials with septa caps to a range of EX and DX autosamplers. The septum piercing capability allows for volatile samples to remained sealed while they await analysis, avoiding unwanted evaporation. Unlike many septa piercing probes, ESI is made from sapphire so there is no risk of contamination from a metal probe, while also maintaining a high strength.

 

The system works by first piercing the septa with the probe until the probe sleeve creates a small path for air to flow. This path prevents the creation of a vacuum inside the vial during the sampling which can cause cavitation of some samples. Once the sampling is complete the probe withdraws while a retaining arm holds the vial in place. To prevent accidents, the software can detect when an obstruction is met. For example, this can prevent damage to the probe if a vial with a non-septa cap is mistakenly placed in the rack.

Septum Piercing Kit

Sample Racks, Vials & Microplate




Sample Racks

21 Position Micro Sample Rack
MR-21-14
14mm diameter - Fits 1mL, 2mL, & 4mL vials
(Fits: V-14-0311CG, V-14-0312CG, V-14-0314CG, V-14-0712, VPC-14-0712)

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Graduated PFA Micro Vial with Conical Bottom

1mL volume, brim full 2mL
V-14-0311CG-X - Qty 10

2mL volume, brim full 3mL
V-14-0312CG-X - Qty 10

4mL volume, brim full 4.5mL
V-14-0314CG-X - Qty 10

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X-Piercing Microplate

This rigid plastic microplate cover is primarily used to protect against environmental contamination.

96-well, 500μL microplate, polystyrene
MT-96-500-05-V - Qty 5

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