microFAST Single Cell - Complete Solution for Single Cell ICPMS Applications

The ability to introduce single cells into an ICPMS and measure the elemental content in each cell, or tagged to each cell, accurately takes a dedicated, well-designed sample introduction system. Having this ability allows for investigators to better understand how much of a specific nanoparticle, metallodrug, or metal-based compound enters the cell. These cells or nanoparticles will vary in size from a few nm’s up to a few 100 μm’s. The typical cell types of interest will vary and with that the stability of the cell-line also varies, such that a gentle, controlled nebulization must be employed in order to not disrupt or lyse the cell.

Complete system includes:
  • microFAST Single Cell Autosampler
  • Offered in two different orientations - left-handed or right-handed
  • Single Cell Introduction Kit
  • CytoNeb
  • CytoSpray
  • One-piece torch
Benefits:
  • Flexible sample volumes - μL to mL of sample
  • Ensure cells stay intact, no cell lysing
  • Low pressure sample introduction
  • High transport efficiency

Capabilities  Applications  Accessories  Specifications

One sample was prepared with 100,000 Ta-tagged cells/mL solution.

Replicate measurements were taken from the same sample to produce this plot.

Transport efficiency for this example: 83.4%

PBMC Ta-tagged cell size: ~ 7.5 μm

Ten 50 nm Au NPs solutions were prepared and analyzed over an 8 day period.

Data points represent average value for each sample over the 8 day period.

Error bars represent ± 1 SD over the 8 days.

Typical transport efficiency: 80-100%


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