hydrideFAST 2 - Simple, Accurate, and Fast Hydride Generation for ICP

hydrideFAST is an online sample introduction system that minimizes the complexity of previous hydride generators while offering high sensitivity. The hydrideFAST 2 version offers the same advantages as hydrideFAST 1, as well as simultaneous generation of both nebulized sample aerosol and hydride gases, introducing both into an ICP instrument at the same time for maximized sensitivity and productivity. At the heart of the hydrideFAST are two key components: the MP² Precision Micro Peripump for stable mixing and the patent-pending hydrideFAST Gas Liquid Separator.

MP² Peripump
Designed with ICP and ICPMS applications in mind, the MP² micro peripump uses a combination of acidresistant ceramic pins with long-life precision polymer rollers to deliver sample and reagents smoothly at flow rates ranging from sub microliter-per-minute to > 10 milliliters per minute.

Gas Liquid Separator
ESI has developed the smallest, highest-performing and most stable gas liquid separator on the market for the hydrideFAST system. All connections are conveniently and securely made using threaded quartz connectors. The design promotes rapid mixing of sample with hydride reagents, promoting a more complete reaction and separation of hydride gases from sample liquids in a small volume.

Measure All ICP Elements Plus Hydride Generation
Traditionally, analyzing hydride-forming elements requires a dedicated machine, meaning all nonhydride elements present in the sample cannot be measured. But with hydrideFAST 2, all elements can be analyzed at the same time with a single instrument. This allows for fewer and faster sample runs.

The Highest Level of Stability
When hydrides form, a considerable amount of hydrogen gas is created as well. With other systems, the amount of hydrogen gas formed over time can vary, causing issues with system sensitivity. The MP² pump on the hydrideFAST system ensures precision addition of hydride reagents providing constant formation of both analyte hydrides and hydrogen gas, promoting a remarkably stable ICP and further improved detection limits.

Features and Benefits of hydrideFAST:

• MP² Peripump
  - Stable signal for improved detection limits
  - Stable hydrogen gas formation
• Gas-Liquid Separator
  - Enhances sensitivity
  - Small internal volume for low memory effect and fast washout
• Small Size
  - Conserves lab space
• Integrated, Modular Design
  - Tames tubing
  - Built-in connections
• Clean Samples
  - Sample does not touch peripump tubing so much lower carryover effect

With hydrideFAST 2, extremely low levels of hydride-forming elements can be detected. Calibration curves for As, Se, Sb, and other hydride-forming elements measured with NaBH4 show excellent linearity from 0 to 10 ppb. Hg curves, which showed similar linearity, were measured with SnCl2.

The hydrideFAST 2 system has at least three modes of operation. Switching among the three modes takes only a few minutes and allows optimized application-specific procedures.

• hydrideFAST 2 mode (hydride generation and nebulization)
  Measures all of the sample simultaneously. The sensitivity for hydride-forming elements can be higher than either hydride alone or nebulization alone because both hydride gases and nebulized aerosol contribute to the analytical signal. This mode maintains the high-throughput productivity of the FAST system while producing high sensitivity and low detection limits for hydride-forming elements including As, Se, Sb, and Hg.
• hydrideFAST 1 mode (hydride generation only)
  Provides high sensitivity for hydride-forming elements only. In addition, because the sample is loaded into the FAST valve, memory effects are reduced compared to conventional hydride generation systems.
• FAST mode (nebulization only)
  The FAST-only mode operates as a high-throughput sample introduction system-the most advanced and most integrated system available, with low memory effects and small sample consumption.